DUS1L

Across TCGA cell cohorts, DUS1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,225 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DUS1L-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Cartilage development. Each is linked with DUS1L in more than 15 cancer types. Because this analysis shows association rather than direction, both DUS1L-to-partner and partner-to-DUS1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by DUS1L-low versus DUS1L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUS1L→partner) and Y-score (partner→DUS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.174	+1.018	<.001	<.001	3	16
CNS	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.186	+0.939	<.001	<.001	3	15
LIVER	Cartilage development →	-0.059	-0.516	.006	.005	3	12
SOFT_TISSUE	Negative regulation of DNA-templated transcription, elongation →	+0.122	+0.842	<.001	<.001	3	11
BONE	Leading strand elongation →	+0.174	+0.937	<.001	<.001	3	11
BONE	Pre-mRNA catabolic process →	+0.224	+1.024	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,225 associations by consensus.

Regulation of transcription of nucleolar large rRNA by RNA polymerase I by DUS1L expression — BONE

Explore this box plot interactively →