DUS1L

Across TCGA cell cohorts, DUS1L mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DUS1L-associated genes across cancer lineages are MAGEB4, FTHL17, and STRA8. Each is linked with DUS1L in more than 1 cancer types. Because this analysis shows association rather than direction, both DUS1L-to-partner and partner-to-DUS1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by DUS1L-low versus DUS1L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUS1L→partner) and Y-score (partner→DUS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.029	+5.415	<.001	.004	3	1
LARGE_INTESTINE	FTHL17 →	+0.081	+5.415	<.001	.004	3	1
LARGE_INTESTINE	STRA8 →	+0.215	+5.415	<.001	.004	3	1
LARGE_INTESTINE	ZNF804B →	+0.022	+5.415	<.001	.004	3	1
LARGE_INTESTINE	OR2J1 →	+0.006	+6.022	<.001	.001	3	1
LARGE_INTESTINE	DAZ2 →	+0.336	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MAGEB4 by DUS1L expression — LARGE_INTESTINE

Explore this box plot interactively →