DTYMK

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DTYMK protein abundance is significantly associated with the RNA expression of many other genes, with 11,519 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DTYMK-associated genes across cancer lineages are FARSB, HJURP, and CENPI. Each is linked with DTYMK in more than 8 cancer types. Because this analysis shows association rather than direction, both DTYMK-to-partner and partner-to-DTYMK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTYMK versus FARSB in LSCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTYMK→partner) and Y-score (partner→DTYMK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCFARSB →+0.461+0.276<.001<.00139
GBMHJURP →+0.978+0.349.001<.00139
LUADCENPI →+0.880+0.312.001<.00138
UCECCENPA →+0.868+0.248<.001<.00138
PDACBRCA1 →+0.688+0.322<.001<.00138
GBMCKAP2L →+0.821+0.308.003<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,519 associations by consensus.

DTYMK vs FARSB — LSCC

Per-sample scatter of DTYMK vs FARSB in LSCC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration