DTYMK

Across TCGA cell cohorts, DTYMK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,104 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DTYMK-associated GO terms across cancer lineages are Thymidine biosynthetic process, 2'-deoxyribonucleoside biosynthetic process, and Pyrimidine deoxyribonucleoside biosynthetic process. Each is linked with DTYMK in more than 18 cancer types. Because this analysis shows association rather than direction, both DTYMK-to-partner and partner-to-DTYMK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Thymidine biosynthetic process grouped by DTYMK-low versus DTYMK-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DTYMK→partner) and Y-score (partner→DTYMK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Thymidine biosynthetic process →	+0.210	+1.342	<.001	<.001	3	19
BLOOD_Myeloma	2'-deoxyribonucleoside biosynthetic process →	+0.210	+1.342	<.001	<.001	3	19
BLOOD_Myeloma	Pyrimidine deoxyribonucleoside biosynthetic process →	+0.210	+1.342	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Nuclear DNA replication →	+0.132	+1.234	.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome segregation →	+0.141	+1.184	<.001	<.001	3	18
OESOPHAGUS	Mitotic spindle elongation →	+0.291	+1.201	.003	.006	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,104 associations by consensus.

Thymidine biosynthetic process by DTYMK expression — BLOOD_Myeloma

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