DTX3L

Across TCGA patient cohorts, DTX3L RNA expression is significantly associated with the protein abundance of many other proteins, with 9,309 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DTX3L-associated proteins across cancer lineages are UBE2L6, NMI, and OAS2. Each is linked with DTX3L in more than 9 cancer types. Because this analysis shows association rather than direction, both DTX3L-to-partner and partner-to-DTX3L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTX3L versus UBE2L6 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DTX3L→partner) and Y-score (partner→DTX3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UBE2L6 →	+0.769	+0.665	<.001	<.001	3	10
LSCC	NMI →	+0.544	+0.764	<.001	<.001	3	10
HNSC	OAS2 →	+0.969	+0.731	<.001	.003	3	10
PDAC	OAS3 →	+0.649	+0.484	<.001	<.001	3	10
COAD	PARP14 →	+0.519	+0.808	<.001	<.001	3	10
COAD	STAT1 →	+0.747	+0.774	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,309 associations by consensus.

DTX3L vs UBE2L6 — HNSC

Explore this scatter interactively →