DTX3L

Across TCGA patient cohorts, DTX3L protein abundance is significantly associated with the RNA expression of many other genes, with 11,789 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DTX3L-associated genes across cancer lineages are ETV7, DDX58, and OAS2. Each is linked with DTX3L in more than 9 cancer types. Because this analysis shows association rather than direction, both DTX3L-to-partner and partner-to-DTX3L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTX3L versus ETV7 in BRCA, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTX3L→partner) and Y-score (partner→DTX3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ETV7 →	+1.255	+0.420	<.001	<.001	3	10
BRCA	DDX58 →	+1.086	+0.429	<.001	<.001	3	10
BRCA	OAS2 →	+1.452	+0.427	<.001	<.001	3	10
OV	IFIH1 →	+1.122	+0.547	<.001	<.001	3	10
BRCA	STAT1 →	+1.146	+0.424	<.001	<.001	3	10
COAD	NMI →	+1.002	+0.481	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,789 associations by consensus.

DTX3L vs ETV7 — BRCA

Explore this scatter interactively →