DTX3

Across TCGA patient cohorts, DTX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,637 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DTX3-associated proteins across cancer lineages are MAP1A, TP53BP1_S552, and HDGFL3. Each is linked with DTX3 in more than 7 cancer types. Because this analysis shows association rather than direction, both DTX3-to-partner and partner-to-DTX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTX3 versus MAP1A in UCEC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DTX3→partner) and Y-score (partner→DTX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAP1A →	+0.521	+0.590	.002	.009	3	8
HNSC	TP53BP1_S552 →	+0.491	+0.857	<.001	<.001	3	7
COAD	HDGFL3 →	+0.625	+0.741	<.001	<.001	3	7
HNSC	TP53BP1_S1114 →	+0.321	+0.740	<.001	<.001	3	7
LSCC	MLKL →	-0.635	-0.690	<.001	<.001	3	6
BRCA	TP53BP1 →	+0.297	+0.768	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,637 associations by consensus.

DTX3 vs MAP1A — UCEC

Explore this scatter interactively →