DTX1

Across TCGA patient cohorts, DTX1 protein abundance is significantly associated with the RNA expression of many other genes, with 402 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DTX1-associated genes across cancer lineages are CST8, MIR302C, and ANXA13. Each is linked with DTX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DTX1-to-partner and partner-to-DTX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTX1 versus CST8 in BRCA, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTX1→partner) and Y-score (partner→DTX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CST8 →	+0.506	+3.219	<.001	.008	3	1
BRCA	MIR302C →	+1.686	+3.219	.006	.008	3	1
GBM	ANXA13 →	+0.402	+0.363	.007	.004	3	1
GBM	NHP2P1 →	+0.841	+0.363	.003	.004	3	1
GBM	CCDC6 →	+0.738	+0.363	.001	.004	3	1
GBM	PARP11 →	+0.669	+0.363	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 402 associations by consensus.

DTX1 vs CST8 — BRCA

Explore this scatter interactively →