DTX1

Across TCGA cell cohorts, DTX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,267 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DTX1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Aerobic respiration. Each is linked with DTX1 in more than 11 cancer types. Because this analysis shows association rather than direction, both DTX1-to-partner and partner-to-DTX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by DTX1-low versus DTX1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DTX1→partner) and Y-score (partner→DTX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of myoblast fusion →	+0.107	+1.149	<.001	<.001	3	12
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.096	+1.266	<.001	<.001	3	12
OESOPHAGUS	Aerobic respiration →	+0.120	+0.682	<.001	.008	3	11
OESOPHAGUS	Regulation of myoblast fusion →	+0.139	+0.689	<.001	.006	3	11
URINARY_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.091	+0.451	<.001	.002	2	12
OESOPHAGUS	Oxidative phosphorylation →	+0.159	+0.950	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,267 associations by consensus.

Negative regulation of myoblast fusion by DTX1 expression — OVARY

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