Across TCGA patient cohorts, DTHD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,984 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DTHD1-associated proteins across cancer lineages are SAMHD1, PIP4K2A, and ARHGAP9_S113. Each is linked with DTHD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DTHD1-to-partner and partner-to-DTHD1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DTHD1→partner) and Y-score (partner→DTHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SAMHD1 →	+0.478	+0.988	<.001	<.001	3	8
HNSC	PIP4K2A →	+0.408	+0.987	<.001	<.001	3	7
BRCA	ARHGAP9_S113 →	+0.614	+0.536	.002	<.001	3	7
COAD	PRKCB →	+0.599	+0.462	<.001	<.001	3	7
BRCA	PSMB10 →	+0.453	+0.366	<.001	<.001	3	7
HNSC	PTPN6 →	+0.513	+1.087	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,984 associations by consensus.

Exploration

DTHD1 survival (RNA) · tumor vs normal (RNA) · all DTHD1 data types