DTD2

Across TCGA patient cohorts, DTD2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,940 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DTD2-associated genes across cancer lineages are THBD, ARMCX4, and SERPINB1. Each is linked with DTD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DTD2-to-partner and partner-to-DTD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTD2 versus THBD in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTD2→partner) and Y-score (partner→DTD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	THBD →	+0.991	+0.321	.004	.009	3	4
UCEC	ARMCX4 →	-1.587	-1.437	.001	.001	3	3
UCEC	SERPINB1 →	+1.656	+1.214	.001	<.001	3	3
UCEC	LINC02595 →	-1.316	-1.215	.001	<.001	3	3
PDAC	ITSN1 →	-0.549	-0.640	<.001	<.001	3	3
LUAD	HBA2 →	+1.878	+0.376	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,940 associations by consensus.

DTD2 vs THBD — HNSC

Explore this scatter interactively →