DTD1-AS1

Across TCGA pan-cancer cohorts, DTD1-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated DTD1-AS1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher DTD1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DTD1-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

LUSC, THCA, and MESO are the cancer types where DTD1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	II,III,IV	0.203	0.801	<.001	84	view →
THCA	DFS	Tertile	II,III,IV	0.223	0.804	<.001	78	view →
MESO	OS	Tertile	All	0.084	0.560	<.001	45	view →
KIRP	DFS	Tertile	All	0.306	0.665	<.001	36	view →
ACC	DFS	Tertile	All	0.208	0.601	.023	24	view →
UVM	DFS	Tertile	All	0.355	0.787	.012	18	view →
HNSC	DFS	Tertile	All	0.743	0.599	.015	18	view →
LUAD	DFS	Tertile	IV	0.539	0.978	.006	18	view →
SKCM	OS	Tertile	All	0.947	0.860	.010	15	view →
LIHC	OS	Tertile	III,IV	0.185	0.622	.016	9	view →
STAD	DFS	Median	III,IV	0.390	0.577	.016	8	view →
ESCA	OS	Quartile	All	0.513	0.709	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

DTD1-AS1–LUSC (OS)

Open the LUSC breakdown →