DSTNP1

Across TCGA pan-cancer cohorts, DSTNP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of DSTNP1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where DSTNP1 RNA is repressed in tumor relative to normal tissue. In most cancer types DSTNP1 is over-expressed in tumor, although a few such as UCEC and THCA show the opposite, repressed pattern.

UCEC, THCA, and LIHC are the cancer types where DSTNP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DSTNP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.863	<.001	8	view →
THCA	Female	All	−0.456	<.001	6	view →
LIHC	Female	II,III,IV	+0.424	<.001	5	view →
COAD	Female	II,III,IV	−0.473	.004	4	view →
BRCA	Female	All	−0.352	.001	4	view →
KICH	All	All	−0.470	<.001	3	view →
CHOL	Male	All	+1.685	<.001	2	view →
LUSC	All	All	−0.325	.012	2	view →
PRAD	All	All	−0.297	.005	2	view →
KIRC	All	All	+0.226	.012	2	view →
ESCA	Female	All	+0.756	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

DSTNP1–UCEC

Open the UCEC breakdown →