DSTN

Across TCGA patient cohorts, DSTN RNA expression is significantly associated with the protein abundance of many other proteins, with 11,863 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DSTN-associated proteins across cancer lineages are THEMIS2, PTPN6, and PTPRC. Each is linked with DSTN in more than 5 cancer types. Because this analysis shows association rather than direction, both DSTN-to-partner and partner-to-DSTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSTN versus THEMIS2 in LSCC, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSTN→partner) and Y-score (partner→DSTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	THEMIS2 →	-0.469	-0.547	<.001	<.001	3	5
BRCA	PTPN6 →	-0.304	-0.527	<.001	<.001	3	5
UCEC	PTPRC →	-0.619	-0.375	<.001	.004	3	5
COAD	LPP →	+0.414	+0.342	<.001	.002	3	5
UCEC	ARHGAP30 →	-0.450	-0.465	.005	.003	2	6
CCRCC	VCL_S726 →	+0.671	+0.374	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,863 associations by consensus.

DSTN vs THEMIS2 — LSCC

Explore this scatter interactively →