DSTN

Across TCGA patient cohorts, DSTN protein abundance is significantly associated with the RNA expression of many other genes, with 12,352 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DSTN-associated genes across cancer lineages are LMOD1, CNN1, and MYH11. Each is linked with DSTN in more than 8 cancer types. Because this analysis shows association rather than direction, both DSTN-to-partner and partner-to-DSTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSTN versus LMOD1 in UCEC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DSTN→partner) and Y-score (partner→DSTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LMOD1 →	+1.499	+0.405	<.001	<.001	3	9
UCEC	CNN1 →	+2.240	+0.527	<.001	<.001	3	8
UCEC	MYH11 →	+2.214	+0.448	<.001	<.001	3	8
OV	PLN →	+1.539	+0.535	<.001	<.001	3	8
UCEC	MYL9 →	+1.281	+0.375	<.001	<.001	3	7
COAD	CASQ2 →	+1.928	+0.554	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,352 associations by consensus.

DSTN vs LMOD1 — UCEC

Explore this scatter interactively →