DSTN

Across TCGA cell cohorts, DSTN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,808 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DSTN-associated GO terms across cancer lineages are Actin filament fragmentation, Response to calcium ion, and Regulation of proteolysis. Each is linked with DSTN in more than 9 cancer types. Because this analysis shows association rather than direction, both DSTN-to-partner and partner-to-DSTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament fragmentation grouped by DSTN-low versus DSTN-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DSTN→partner) and Y-score (partner→DSTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Actin filament fragmentation →	+0.155	+1.576	<.001	<.001	3	10
BONE	Response to calcium ion →	+0.113	+1.395	<.001	<.001	3	10
BONE	Regulation of proteolysis →	+0.093	+1.343	<.001	<.001	3	10
STOMACH	Regulation by virus of viral protein levels in host cell →	+0.166	+0.894	<.001	.001	3	9
BONE	Regulation of cell-substrate adhesion →	+0.122	+1.586	<.001	<.001	3	9
BONE	Cardiac chamber development →	+0.097	+1.473	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,808 associations by consensus.

Actin filament fragmentation by DSTN expression — BLOOD_Lymphoma

Explore this box plot interactively →