DSPP

Across TCGA cell cohorts, DSPP RNA expression is significantly associated with the RNA expression of many other genes, with 3,521 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible DSPP-associated genes across cancer lineages are DMP1, TRAPPC10, and FCHSD1. Each is linked with DSPP in more than 8 cancer types. Because this analysis shows association rather than direction, both DSPP-to-partner and partner-to-DSPP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSPP versus DMP1 in OESOPHAGUS, with a Pearson correlation of 0.47.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DSPP→partner) and Y-score (partner→DSPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DMP1 →	+0.135	+0.062	.002	.002	2	9
BREAST	TRAPPC10 →	+0.878	+0.030	<.001	.001	3	3
LUNG_SCLC	FCHSD1 →	+2.083	+0.050	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	VPS52 →	+0.715	+0.025	.001	.006	2	4
BREAST	SPDYE6 →	+0.908	+0.021	.001	.003	3	3
KIDNEY	TAS2R4 →	+0.482	+0.022	<.001	.007	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,521 associations by consensus.

DSPP vs DMP1 — OESOPHAGUS

Explore this scatter interactively →