DSG1

Across TCGA patient cohorts, DSG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,890 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DSG1-associated proteins across cancer lineages are TRIM29, PHLDB3_S254, and DSC2_S873. Each is linked with DSG1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DSG1-to-partner and partner-to-DSG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSG1 versus TRIM29 in BRCA, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSG1→partner) and Y-score (partner→DSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRIM29 →	+1.621	+1.667	<.001	<.001	3	4
HNSC	PHLDB3_S254 →	+0.439	+1.881	<.001	<.001	3	4
LSCC	DSC2_S873 →	+0.959	+1.213	<.001	<.001	3	4
UCEC	PKP1_S185 →	+3.022	+1.402	<.001	.005	3	4
HNSC	DSC2 →	+1.014	+2.961	<.001	<.001	3	4
LSCC	DSP_S178 →	+1.117	+1.311	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,890 associations by consensus.

DSG1 vs TRIM29 — BRCA

Explore this scatter interactively →