DSE

Across TCGA patient cohorts, DSE RNA expression is significantly associated with the RNA expression of many other genes, with 19,651 significant associations in total. THYM shows the largest number of these associations.

The most reproducible DSE-associated genes across cancer lineages are ACVR1, ITGA4, and PLXDC2. Each is linked with DSE in more than 32 cancer types. Because this analysis shows association rather than direction, both DSE-to-partner and partner-to-DSE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSE versus ACVR1 in THYM, with a Pearson correlation of 0.90.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DSE→partner) and Y-score (partner→DSE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	ACVR1 →	+1.429	+1.609	<.001	<.001	3	33
DLBC	ITGA4 →	+1.944	+0.999	<.001	<.001	3	33
THYM	PLXDC2 →	+1.872	+1.516	<.001	<.001	3	33
THYM	DOCK4 →	+1.456	+1.533	<.001	<.001	3	33
DLBC	SEC31A →	+1.243	+1.179	<.001	<.001	3	33
THYM	ITGB1 →	+2.357	+1.641	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,651 associations by consensus.

DSE vs ACVR1 — THYM

Explore this scatter interactively →