DSE

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DSE RNA expression is significantly associated with the protein abundance of many other proteins, with 22,562 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DSE-associated proteins across cancer lineages are CRTAP, DPYD, and TBC1D2B. Each is linked with DSE in more than 9 cancer types. Because this analysis shows association rather than direction, both DSE-to-partner and partner-to-DSE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSE versus CRTAP in OV, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSE→partner) and Y-score (partner→DSE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCRTAP →+0.760+0.968<.001<.001310
GBMDPYD →+0.942+0.607<.001<.001310
GBMTBC1D2B →+0.416+0.784<.001<.001310
COADZYX →+0.510+0.821<.001<.00139
COADRCN3 →+0.682+0.601<.001<.00139
OVC1QB →+0.709+0.779<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 22,562 associations by consensus.

DSE vs CRTAP — OV

Per-sample scatter of DSE vs CRTAP in OV (Pearson r = 0.51).

Explore this scatter interactively →

Exploration