DSE

Across TCGA patient cohorts, DSE protein abundance is significantly associated with the protein abundance of many other proteins, with 26,991 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DSE-associated proteins across cancer lineages are PLAU, ANO6_S256, and ANPEP. Each is linked with DSE in more than 3 cancer types. Because this analysis shows association rather than direction, both DSE-to-partner and partner-to-DSE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSE versus PLAU in LUAD, with a Pearson correlation of 0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSE→partner) and Y-score (partner→DSE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PLAU →	+0.790	+0.372	<.001	<.001	3	4
GBM	ANO6_S256 →	+1.225	+0.851	.001	<.001	3	3
PDAC	ANPEP →	+0.633	+0.559	.002	<.001	3	3
LSCC	CCAR1 →	-0.232	-0.396	<.001	.002	3	3
PDAC	CHPF2_S64 →	+1.242	+0.885	<.001	<.001	3	3
PDAC	CKAP4 →	+0.375	+0.428	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,991 associations by consensus.

DSE vs PLAU — LUAD

Explore this scatter interactively →