DSCR9

Across TCGA pan-cancer cohorts, DSCR9 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of DSCR9’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where DSCR9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DSCR9 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KIRC, BLCA, and LIHC are the cancer types where DSCR9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DSCR9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.143	<.001	12	view →
BLCA	All	All	+0.270	<.001	9	view →
LIHC	Female	II,III,IV	+0.181	<.001	9	view →
HNSC	All	All	+0.134	<.001	8	view →
COAD	All	All	+0.153	<.001	7	view →
UCEC	All	All	+0.341	<.001	6	view →
LUSC	All	All	+0.287	<.001	6	view →
STAD	All	II,III,IV	+0.179	<.001	6	view →
LUAD	Female	All	+0.158	<.001	6	view →
BRCA	All	All	+0.152	<.001	6	view →
READ	All	II,III,IV	+0.220	.016	4	view →
ESCA	All	II,III,IV	+0.415	.036	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

DSCR9–KIRC

Open the KIRC breakdown →