Across TCGA pan-cancer cohorts, DSCR4-IT1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of DSCR4-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where DSCR4-IT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DSCR4-IT1 is over-expressed in tumor.

LIHC, STAD, and LUAD are the cancer types where DSCR4-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DSCR4-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.276	.008	3	view →
STAD	All	All	+0.206	.042	1	view →
LUAD	All	All	+0.055	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: DSCR4-IT1 RNA expression & survival · all DSCR4-IT1 data types