DSCC1

Across TCGA patient cohorts, DSCC1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,630 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DSCC1-associated genes across cancer lineages are CDKN3, CENPM, and POLE2. Each is linked with DSCC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DSCC1-to-partner and partner-to-DSCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSCC1 versus CDKN3 in UCEC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DSCC1→partner) and Y-score (partner→DSCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDKN3 →	+1.040	+0.489	<.001	<.001	3	8
UCEC	CENPM →	+1.000	+0.342	<.001	<.001	3	7
HNSC	POLE2 →	+0.953	+0.393	<.001	.001	3	7
UCEC	GINS1 →	+1.134	+0.579	<.001	<.001	3	7
LSCC	CENPI →	+1.030	+0.661	<.001	<.001	3	7
UCEC	MCM4 →	+0.877	+0.514	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,630 associations by consensus.

DSCC1 vs CDKN3 — UCEC

Explore this scatter interactively →