DSCC1

Across TCGA cell cohorts, DSCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,797 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DSCC1-associated GO terms across cancer lineages are Positive regulation of DNA-directed DNA polymerase activity, Protein localization to condensed chromosome, and DNA strand elongation. Each is linked with DSCC1 in more than 19 cancer types. Because this analysis shows association rather than direction, both DSCC1-to-partner and partner-to-DSCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA-directed DNA polymerase activity grouped by DSCC1-low versus DSCC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DSCC1→partner) and Y-score (partner→DSCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA-directed DNA polymerase activity →	+0.284	+1.854	<.001	<.001	3	20
OESOPHAGUS	Protein localization to condensed chromosome →	+0.211	+1.743	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.201	+1.822	<.001	<.001	3	20
OESOPHAGUS	Maintenance of sister chromatid cohesion →	+0.227	+1.785	<.001	<.001	3	20
OESOPHAGUS	Maintenance of mitotic sister chromatid cohesion →	+0.227	+1.785	<.001	<.001	3	20
BLOOD_Myeloma	Regulation of centrosome cycle →	+0.096	+1.901	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,797 associations by consensus.

Positive regulation of DNA-directed DNA polymerase activity by DSCC1 expression — BONE

Explore this box plot interactively →