DSCAML1

Across TCGA cell cohorts, DSCAML1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,942 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DSCAML1-associated GO terms across cancer lineages are Demethylation, Positive regulation of intracellular estrogen receptor signaling pathway, and Aminoglycan metabolic process. Each is linked with DSCAML1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DSCAML1-to-partner and partner-to-DSCAML1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Demethylation grouped by DSCAML1-low versus DSCAML1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DSCAML1→partner) and Y-score (partner→DSCAML1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Demethylation →	-0.071	-1.252	.003	.001	3	5
LUNG_SCLC	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.150	+1.326	.002	.005	3	5
LUNG_SCLC	Aminoglycan metabolic process →	-0.070	-1.368	.004	.001	3	5
BREAST	Regulation of myoblast fusion →	+0.078	+0.432	<.001	.006	3	5
BREAST	Presynaptic active zone organization →	-0.134	-0.522	<.001	.002	3	5
BLOOD_Leukemia	Regulation of tetrapyrrole biosynthetic process →	-0.103	-0.341	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,942 associations by consensus.

Demethylation by DSCAML1 expression — KIDNEY

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