DSC3

Across TCGA cell cohorts, DSC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,582 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible DSC3-associated GO terms across cancer lineages are Axoneme assembly, Molting cycle, and Hair cycle. Each is linked with DSC3 in more than 5 cancer types. Because this analysis shows association rather than direction, both DSC3-to-partner and partner-to-DSC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Axoneme assembly grouped by DSC3-low versus DSC3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DSC3→partner) and Y-score (partner→DSC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Axoneme assembly →	-0.039	-1.622	<.001	<.001	3	6
BREAST	Molting cycle →	+0.228	+2.513	<.001	<.001	3	6
BREAST	Hair cycle →	+0.228	+2.513	<.001	<.001	3	6
BREAST	Negative regulation of T cell differentiation →	+0.166	+2.574	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Establishment of protein localization to organelle →	+0.031	+1.274	<.001	<.001	3	6
OVARY	Adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway →	+0.048	+0.914	.002	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,582 associations by consensus.

Axoneme assembly by DSC3 expression — BREAST

Explore this box plot interactively →