DRP2

Across TCGA patient cohorts, DRP2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,887 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DRP2-associated genes across cancer lineages are SEC14L2, IL2RB, and ASB2. Each is linked with DRP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DRP2-to-partner and partner-to-DRP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DRP2 versus SEC14L2 in GBM, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRP2→partner) and Y-score (partner→DRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEC14L2 →	+0.458	+0.490	.007	<.001	3	1
GBM	IL2RB →	-0.603	-0.426	<.001	.008	3	1
GBM	ASB2 →	-0.325	-0.323	.004	.002	3	1
GBM	ZFYVE21 →	+0.510	+0.522	<.001	<.001	3	1
GBM	VSX1 →	+0.591	+0.308	<.001	.003	3	1
GBM	CD40 →	-0.673	-0.448	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,887 associations by consensus.

DRP2 vs SEC14L2 — GBM

Explore this scatter interactively →