DRP2

Across TCGA patient cohorts, DRP2 mutation is significantly associated with the RNA expression of many other genes, with 2,501 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DRP2-associated genes across cancer lineages are CDADC1, SEC24A, and SLC25A30. Each is linked with DRP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DRP2-to-partner and partner-to-DRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDADC1 grouped by DRP2-low versus DRP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRP2→partner) and Y-score (partner→DRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDADC1 →	+0.257	+1.434	.001	<.001	3	4
UCEC	SEC24A →	+0.386	+1.311	.002	.005	3	3
UCEC	SLC25A30 →	+0.322	+1.430	.002	.002	3	3
SARC	LINC00686 →	+0.286	+4.620	.004	.007	3	3
COAD	ELAVL4-AS1 →	+0.111	+4.187	<.001	.001	3	2
CESC	MRPS17P3 →	+0.079	+2.746	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,501 associations by consensus.

CDADC1 by DRP2 expression — UCEC

Explore this box plot interactively →