DRP2

Across TCGA cell cohorts, DRP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,386 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DRP2-associated GO terms across cancer lineages are Microtubule polymerization, Mitotic cytokinesis, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with DRP2 in more than 12 cancer types. Because this analysis shows association rather than direction, both DRP2-to-partner and partner-to-DRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by DRP2-low versus DRP2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DRP2→partner) and Y-score (partner→DRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule polymerization →	+0.107	+0.332	.001	<.001	3	13
LARGE_INTESTINE	Mitotic cytokinesis →	+0.074	+0.290	<.001	<.001	3	12
BREAST	Regulation of metaphase/anaphase transition of cell cycle →	+0.109	+0.333	<.001	<.001	3	12
BLOOD_Leukemia	Cell division →	+0.077	+0.711	<.001	<.001	3	11
OESOPHAGUS	Cytoskeleton-dependent cytokinesis →	+0.075	+0.263	.004	.009	3	11
OESOPHAGUS	Centrosome cycle →	+0.076	+0.199	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,386 associations by consensus.

Microtubule polymerization by DRP2 expression — LARGE_INTESTINE

Explore this box plot interactively →