DRGX

Across TCGA patient cohorts, DRGX RNA expression is significantly associated with the go_rna of many other GO terms, with 6,807 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DRGX-associated GO terms across cancer lineages are Positive regulation of type II interferon production, Neuron apoptotic process, and Regulation of leukocyte mediated immunity. Each is linked with DRGX in more than 10 cancer types. Because this analysis shows association rather than direction, both DRGX-to-partner and partner-to-DRGX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of type II interferon production grouped by DRGX-low versus DRGX-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DRGX→partner) and Y-score (partner→DRGX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of type II interferon production →	+0.051	+0.055	.001	.007	2	11
DLBC	Neuron apoptotic process →	+0.041	+0.070	<.001	<.001	3	9
LUAD	Regulation of leukocyte mediated immunity →	+0.023	+0.511	<.001	.001	2	10
GBM	Regulated exocytosis →	+0.029	+0.182	<.001	<.001	3	9
GBM	Positive regulation of exocytosis →	+0.038	+0.128	<.001	<.001	2	10
ESCA	Interleukin-4-mediated signaling pathway →	+0.082	+0.398	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,807 associations by consensus.

Positive regulation of type II interferon production by DRGX expression — DLBC

Explore this box plot interactively →