DRGX

Across TCGA cell cohorts, DRGX RNA expression is significantly associated with the go_rna of many other GO terms, with 1,046 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DRGX-associated GO terms across cancer lineages are Protein localization to endosome, Negative regulation of synaptic plasticity, and Xenobiotic transport. Each is linked with DRGX in more than 5 cancer types. Because this analysis shows association rather than direction, both DRGX-to-partner and partner-to-DRGX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to endosome grouped by DRGX-low versus DRGX-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DRGX→partner) and Y-score (partner→DRGX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein localization to endosome →	+0.093	+0.142	<.001	.002	3	6
SOFT_TISSUE	Negative regulation of synaptic plasticity →	-1.000	-1.225	<.001	<.001	3	5
SOFT_TISSUE	Xenobiotic transport →	-0.074	-1.086	<.001	<.001	3	5
SOFT_TISSUE	Regulation of gastrulation →	-0.186	-1.270	<.001	.009	3	4
BREAST	Actin crosslink formation →	+0.122	+0.047	<.001	.009	3	4
BREAST	Neurotransmitter transport →	-0.058	-0.049	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,046 associations by consensus.

Protein localization to endosome by DRGX expression — PANCREAS

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