DRGX

Across TCGA cell cohorts, DRGX mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DRGX-associated genes across cancer lineages are IFNA10, GALP, and COX4I2. Each is linked with DRGX in more than 1 cancer types. Because this analysis shows association rather than direction, both DRGX-to-partner and partner-to-DRGX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA10 grouped by DRGX-low versus DRGX-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRGX→partner) and Y-score (partner→DRGX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IFNA10 →	+0.026	+5.415	<.001	.004	3	1
LARGE_INTESTINE	GALP →	+0.026	+6.022	<.001	.001	3	1
LUNG_NSCLC_LUAD	COX4I2 →	+0.098	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR1L3 →	+0.028	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

IFNA10 by DRGX expression — LARGE_INTESTINE

Explore this box plot interactively →