DRG2

Across TCGA patient cohorts, DRG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,147 significant associations in total. THCA shows the largest number of these associations.

The most reproducible DRG2-associated GO terms across cancer lineages are GMP biosynthetic process, mRNA export from nucleus, and XMP metabolic process. Each is linked with DRG2 in more than 25 cancer types. Because this analysis shows association rather than direction, both DRG2-to-partner and partner-to-DRG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP biosynthetic process grouped by DRG2-low versus DRG2-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DRG2→partner) and Y-score (partner→DRG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	GMP biosynthetic process →	+0.055	+0.415	<.001	.001	3	25
SCLC	mRNA export from nucleus →	+0.105	+0.484	.001	.003	3	25
SCLC	XMP metabolic process →	+0.125	+0.443	.006	.006	1	26
ESCA	Regulation of DNA-templated DNA replication →	+0.066	+0.383	<.001	<.001	3	24
THYM	Regulation of lysosome organization →	+0.051	+0.356	<.001	<.001	3	24
THYM	Regulation of DNA replication →	+0.039	+0.341	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,147 associations by consensus.

GMP biosynthetic process by DRG2 expression — DLBC

Explore this box plot interactively →