Across TCGA patient cohorts, DRG1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,136 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DRG1-associated genes across cancer lineages are BUB1, TRIP13, and MYBL2. Each is linked with DRG1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DRG1-to-partner and partner-to-DRG1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRG1→partner) and Y-score (partner→DRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BUB1 →	+0.848	+0.191	<.001	<.001	3	8
LUAD	TRIP13 →	+0.864	+0.196	<.001	<.001	3	8
LUAD	MYBL2 →	+1.729	+0.223	<.001	<.001	3	7
GBM	TTK →	+1.152	+0.224	<.001	<.001	3	7
BRCA	CENPA →	+1.011	+0.222	<.001	<.001	3	7
GBM	KIF14 →	+1.188	+0.246	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,136 associations by consensus.

Exploration

DRG1 survival (RNA) · tumor vs normal (RNA) · all DRG1 data types