Across TCGA patient cohorts, DRG1 mutation is significantly associated with the RNA expression of many other genes, with 481 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DRG1-associated genes across cancer lineages are TSPY15P, MIR6803, and OR6N2. Each is linked with DRG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DRG1-to-partner and partner-to-DRG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRG1→partner) and Y-score (partner→DRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TSPY15P →	+0.084	+7.741	<.001	.009	3	2
UCEC	MIR6803 →	+0.172	+4.671	<.001	.002	3	2
BLCA	OR6N2 →	+0.077	+5.444	<.001	.002	3	2
SKCM	FAM197Y5 →	+0.029	+7.816	<.001	.008	3	2
BLCA	DHX33-DT →	+0.134	+4.396	.003	.006	3	1
BLCA	MIR4717 →	+0.288	+4.788	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 481 associations by consensus.

Exploration

DRG1 survival (RNA) · tumor vs normal (RNA) · all DRG1 data types