Across TCGA pan-cancer cohorts, DRD5P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of DRD5P1’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where DRD5P1 RNA is repressed in tumor relative to normal tissue. In most cancer types DRD5P1 is over-expressed in tumor, although a few such as STAD and BRCA show the opposite, repressed pattern.

STAD, BRCA, and ESCA are the cancer types where DRD5P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DRD5P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	−0.241	<.001	9	view →
BRCA	All	All	−0.057	<.001	6	view →
ESCA	All	All	−1.298	.010	1	view →
KIRP	Male	All	−0.010	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: DRD5P1 RNA expression & survival · all DRD5P1 data types