DRD4

Across TCGA patient cohorts, DRD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,309 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DRD4-associated proteins across cancer lineages are PTK7, SEC23B, and AEBP1. Each is linked with DRD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both DRD4-to-partner and partner-to-DRD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DRD4 versus PTK7 in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DRD4→partner) and Y-score (partner→DRD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PTK7 →	+0.533	+0.847	<.001	.001	3	5
LUAD	SEC23B →	-0.241	-0.322	.003	.003	3	4
BRCA	AEBP1 →	+0.650	+0.541	<.001	<.001	3	4
OV	CLINT1 →	-0.283	-0.815	<.001	<.001	3	4
OV	COL12A1 →	+1.072	+0.733	<.001	.009	3	4
OV	FN1 →	+0.903	+0.797	.004	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,309 associations by consensus.

DRD4 vs PTK7 — OV

Explore this scatter interactively →