DRD3

Across TCGA patient cohorts, DRD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,622 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DRD3-associated GO terms across cancer lineages are Positive regulation of GTPase activity, CD4-positive, alpha-beta T cell differentiation, and Immune system development. Each is linked with DRD3 in more than 17 cancer types. Because this analysis shows association rather than direction, both DRD3-to-partner and partner-to-DRD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of GTPase activity grouped by DRD3-low versus DRD3-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DRD3→partner) and Y-score (partner→DRD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of GTPase activity →	+0.067	+0.146	<.001	<.001	3	18
STAD	CD4-positive, alpha-beta T cell differentiation →	+0.058	+0.084	<.001	<.001	3	18
ESCA	Immune system development →	+0.074	+0.120	<.001	<.001	3	17
STAD	T cell differentiation involved in immune response →	+0.056	+0.082	<.001	<.001	3	17
ESCA	TOR signaling →	+0.081	+0.124	<.001	.001	3	17
ESCA	Lymphocyte apoptotic process →	+0.083	+0.122	<.001	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,622 associations by consensus.

Positive regulation of GTPase activity by DRD3 expression — ESCA

Explore this box plot interactively →