DRD3

Across TCGA cell cohorts, DRD3 RNA expression is significantly associated with the RNA expression of many other genes, with 934 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible DRD3-associated genes across cancer lineages are PRAMEF7, OR11H12, and TNP2. Each is linked with DRD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both DRD3-to-partner and partner-to-DRD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DRD3 versus PRAMEF7 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.34.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRD3→partner) and Y-score (partner→DRD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PRAMEF7 →	+0.113	+0.128	.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	OR11H12 →	+0.238	+0.015	<.001	.002	3	4
PANCREAS	TNP2 →	+0.054	+0.004	<.001	<.001	3	4
URINARY_TRACT	OR4F15 →	+0.122	+0.014	.006	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	GK2 →	+0.076	+0.025	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	PRAMEF11 →	+0.163	+0.025	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 934 associations by consensus.

DRD3 vs PRAMEF7 — LUNG_NSCLC_LUSC

Explore this scatter interactively →