Across TCGA patient cohorts, DRD1 mutation is significantly associated with the RNA expression of many other genes, with 3,744 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DRD1-associated genes across cancer lineages are COX10, PFAS, and CIDECP1. Each is linked with DRD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DRD1-to-partner and partner-to-DRD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRD1→partner) and Y-score (partner→DRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COX10 →	+0.460	+2.432	<.001	<.001	3	4
LUAD	PFAS →	+0.661	+3.593	<.001	.001	3	3
UCEC	CIDECP1 →	+0.517	+2.169	<.001	<.001	3	3
UCEC	ZNF724 →	+0.472	+1.934	.002	.002	3	3
UCEC	RPL22P14 →	+0.069	+1.688	.001	.009	3	3
UCEC	PITPNA-AS1 →	+0.593	+2.732	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,744 associations by consensus.

Exploration

DRD1 survival (RNA) · tumor vs normal (RNA) · all DRD1 data types