DRC3

Across TCGA patient cohorts, DRC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,268 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DRC3-associated proteins across cancer lineages are WDR19, IFT122, and WDR35. Each is linked with DRC3 in more than 7 cancer types. Because this analysis shows association rather than direction, both DRC3-to-partner and partner-to-DRC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DRC3 versus WDR19 in BRCA, with a Pearson correlation of 0.78.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DRC3→partner) and Y-score (partner→DRC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WDR19 →	+0.560	+1.487	<.001	<.001	3	8
BRCA	IFT122 →	+0.447	+1.402	<.001	<.001	3	8
BRCA	WDR35 →	+0.457	+1.315	<.001	<.001	3	7
UCEC	CROCC →	+0.468	+1.018	<.001	<.001	3	7
OV	IFT88 →	+0.472	+0.809	.001	.001	3	7
BRCA	LZTFL1 →	+0.750	+1.247	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,268 associations by consensus.

DRC3 vs WDR19 — BRCA

Explore this scatter interactively →