DRC3

Across TCGA patient cohorts, DRC3 protein abundance is significantly associated with the RNA expression of many other genes, with 337 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DRC3-associated genes across cancer lineages are PLEK2, SNW1, and TUBB1. Each is linked with DRC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DRC3-to-partner and partner-to-DRC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DRC3 versus PLEK2 in LUAD, with a Pearson correlation of -0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DRC3→partner) and Y-score (partner→DRC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PLEK2 →	-1.581	-1.063	.004	.005	3	1
LUAD	SNW1 →	-1.009	-2.059	<.001	.004	3	1
LUAD	TUBB1 →	+0.444	+1.083	<.001	.004	3	1
LUAD	SNAPC2 →	-0.719	-1.083	<.001	.004	3	1
LUAD	POP4 →	-0.504	-1.053	.009	.005	3	1
LUAD	TMEM59L →	+2.815	+1.584	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 337 associations by consensus.

DRC3 vs PLEK2 — LUAD

Explore this scatter interactively →