DRC3

Across TCGA cell cohorts, DRC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,685 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DRC3-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of organelle assembly, and Cytoskeleton-dependent intracellular transport. Each is linked with DRC3 in more than 16 cancer types. Because this analysis shows association rather than direction, both DRC3-to-partner and partner-to-DRC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by DRC3-low versus DRC3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DRC3→partner) and Y-score (partner→DRC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.128	+0.976	<.001	<.001	3	17
STOMACH	Regulation of organelle assembly →	+0.055	+0.888	.002	<.001	3	17
OESOPHAGUS	Cytoskeleton-dependent intracellular transport →	+0.059	+0.911	<.001	.001	3	16
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.113	+0.718	.001	<.001	3	16
BLOOD_Lymphoma	Negative regulation of mRNA processing →	+0.098	+0.847	<.001	<.001	3	16
SOFT_TISSUE	Positive regulation of DNA metabolic process →	+0.078	+0.946	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,685 associations by consensus.

Negative regulation of myoblast fusion by DRC3 expression — STOMACH

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