DRAXIN

Across TCGA patient cohorts, DRAXIN RNA expression is significantly associated with the go_rna of many other GO terms, with 7,158 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DRAXIN-associated GO terms across cancer lineages are Positive regulation of proteasomal ubiquitin-dependent protein catabolic process, Negative regulation of gene expression, epigenetic, and Positive regulation of proteasomal protein catabolic process. Each is linked with DRAXIN in more than 23 cancer types. Because this analysis shows association rather than direction, both DRAXIN-to-partner and partner-to-DRAXIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteasomal ubiquitin-dependent protein catabolic process grouped by DRAXIN-low versus DRAXIN-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DRAXIN→partner) and Y-score (partner→DRAXIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.077	+0.601	<.001	<.001	3	23
SCLC	Negative regulation of gene expression, epigenetic →	+0.081	+0.886	<.001	.001	3	23
ESCA	Positive regulation of proteasomal protein catabolic process →	+0.076	+0.701	<.001	<.001	3	23
ESCA	Neural tube formation →	+0.089	+0.912	<.001	<.001	3	22
ESCA	Primary miRNA processing →	+0.066	+0.533	<.001	<.001	3	22
ESCA	Epigenetic regulation of gene expression →	+0.073	+0.689	<.001	<.001	2	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,158 associations by consensus.

Positive regulation of proteasomal ubiquitin-dependent protein catabolic process by DRAXIN expression — ESCA

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