DRAXIN

Across TCGA patient cohorts, DRAXIN protein abundance is significantly associated with the protein abundance of many other proteins, with 742 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DRAXIN-associated proteins across cancer lineages are ATF2_S136, ATXN1L_S251, and BCL11B_S129. Each is linked with DRAXIN in more than 1 cancer types. Because this analysis shows association rather than direction, both DRAXIN-to-partner and partner-to-DRAXIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DRAXIN versus ATF2_S136 in GBM, with a Pearson correlation of 0.35.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DRAXIN→partner) and Y-score (partner→DRAXIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ATF2_S136 →	+0.485	+0.771	.001	.001	3	1
GBM	ATXN1L_S251 →	-0.425	-0.630	.005	<.001	3	1
GBM	BCL11B_S129 →	+1.146	+1.010	.001	.001	3	1
GBM	ADGRB1_S1554 →	+0.677	+1.736	.001	<.001	3	1
GBM	CDC42BPB_S479 →	+0.840	+1.081	<.001	.001	3	1
GBM	ABCB8 →	-0.362	-0.841	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 742 associations by consensus.

DRAXIN vs ATF2_S136 — GBM

Explore this scatter interactively →