DRAXIN

Across TCGA cell cohorts, DRAXIN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,903 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DRAXIN-associated GO terms across cancer lineages are Protein-DNA complex organization, Negative regulation of gene expression, epigenetic, and Heterochromatin organization. Each is linked with DRAXIN in more than 7 cancer types. Because this analysis shows association rather than direction, both DRAXIN-to-partner and partner-to-DRAXIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex organization grouped by DRAXIN-low versus DRAXIN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DRAXIN→partner) and Y-score (partner→DRAXIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein-DNA complex organization →	+0.078	+1.282	<.001	<.001	3	8
LUNG_SCLC	Negative regulation of gene expression, epigenetic →	+0.057	+1.115	.001	.002	3	8
SOFT_TISSUE	Heterochromatin organization →	+0.052	+1.160	<.001	<.001	3	8
BONE	Positive regulation of gene expression, epigenetic →	+0.068	+1.471	.002	.001	3	8
BLOOD_Leukemia	Regulation of G1/S transition of mitotic cell cycle →	+0.057	+1.168	<.001	<.001	3	8
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.102	+1.010	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,903 associations by consensus.

Protein-DNA complex organization by DRAXIN expression — BONE

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