DRAP1

Across TCGA pan-cancer cohorts, DRAP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DRAP1 data layer compared with 28 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher DRAP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DRAP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

PDAC, LSCC, and LUAD are the cancer types where DRAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.839	0.701	.006	16	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.186	.024	10	view →
LUAD	DFS	Tertile	All	0.724	0.502	.022	9	view →
GBM	OS	Tertile	All	0.488	0.249	.006	7	view →
COAD	DFS	Median	III,IV	1.000	0.841	.041	6	view →
CCRCC	OS	Tertile	All	0.881	1.000	.010	5	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DRAP1–PDAC (DFS)

Open the PDAC breakdown →