DRAM2

Across TCGA patient cohorts, DRAM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,160 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DRAM2-associated proteins across cancer lineages are UBA7, RGS10, and CAPZA1. Each is linked with DRAM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both DRAM2-to-partner and partner-to-DRAM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DRAM2 versus UBA7 in BRCA, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DRAM2→partner) and Y-score (partner→DRAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBA7 →	+0.358	+0.555	<.001	<.001	3	5
GBM	RGS10 →	+0.366	+0.353	<.001	<.001	3	4
GBM	CAPZA1 →	+0.276	+0.485	.001	<.001	3	4
PDAC	DNASE2 →	+0.435	+0.300	.003	.004	3	4
LSCC	PRPF38B →	+0.197	+0.356	.004	.001	3	3
HNSC	TRIM33 →	+0.266	+0.823	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,160 associations by consensus.

DRAM2 vs UBA7 — BRCA

Explore this scatter interactively →