DR1

Across TCGA patient cohorts, DR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,617 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DR1-associated proteins across cancer lineages are DRAP1, FNBP1L, and SDF2L1. Each is linked with DR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DR1-to-partner and partner-to-DR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DR1 versus DRAP1 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DR1→partner) and Y-score (partner→DR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DRAP1 →	+0.291	+0.336	.002	<.001	3	6
LSCC	FNBP1L →	+0.440	+0.341	.001	.005	3	4
LUAD	SDF2L1 →	-0.372	-0.330	<.001	.002	3	4
HNSC	MANF →	-0.419	-0.607	<.001	<.001	3	4
COAD	GTF2B →	+0.257	+0.354	.001	.007	3	4
OV	NOSIP →	+0.340	+0.460	.004	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,617 associations by consensus.

DR1 vs DRAP1 — GBM

Explore this scatter interactively →